Adrienne D. Briggs MD

  • Clinical Director, Bone Marrow Transplant Program, Banner Good Samaritan Hospital, Phoenix

https://arizonaoncology.com/locations-physicians/physicians/profile-adrienne-d-briggs-md/

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Damaged valves appear thickened and may not respond normally to Valsalva maneuver treatment quinsy quality epitol 100mg. Respiratory phasicity results from the normal flow velocity changes that occur in response to variation in intrathoracic 2916 Section 6 Chest and Cardiovascular Imaging pressure. The presence of cardiac and respiratory phasicity in a vein suggests patency of the venous system between the thorax and site of insonation. However, respiratory phasicity may not be depressed in patients who are shallow breathers, who have spinal cord injuries and when the thrombosis is partial. Respiratory phasicity may be made more prominent by asking the patient to take a deep breath which results in cessation of flow. Evaluation of phasicity should be performed at both groins to facilitate comparison. Augmentation entails mechanically propelling venous blood from distal portion of an extremity to the point of insonation by squeezing the calf. This results in a rush of blood which is detected by Doppler upstream, and is said to indicate absence of significant obstruction between the site of augmentation and insonation. In the upper extremity unlike the lower extremity, the superficial system is dominant. The basilic vein is technically a part of the superficial system but thrombosis of this vessel is considered clinically significant. The axillary vein may then be traced beneath the pectoralis muscle and into the thoracic outlet at which point it becomes the subclavian vein. The cephalic vein may be visualized at this point as a large vessel entering the deep system from above. Although, the rate of catheter-associated thrombosis has decreased in recent years due to improvement in biocompatibility and better insertion and maintenance techniques. In this situation, anterior scalene hypertrophy causes partial blockage of the subclavian vein. When the thrombus involves those portions of the upper extremity veins which are readily imaged, the diagnosis is straight forward. Large collaterals are often visualized and these should not be confused with the main vein. Spectral evaluation is useful for identification of central thrombosis where the clot may be difficult or impossible to identify. The upper extremity veins normally show a triphasic flow pattern (cardiac pulsatility). Loss of cardiac pulsatility with monophasic flow pattern is strongly suggestive of a more central venous obstruction. Response to Valsalva maneuver or brisk inspiratory sniff can also be observed to assess venous patency. If the patient sniffs, the internal jugular vein or subclavian vein will decrease in diameter and spectral analysis will show an increase in blood velocity.

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The indications may be broadly categorized as diagnostic thoracic medications requiring prior authorization discount epitol 100mg line, diagnostic nonthoracic, echocardiography and interventional procedures, including vascular catheterization. On the radiograph the catheter should be seen in the main pulmonary artery not extending beyond the major hilar vessels. This is because the pulmonary arteries narrow in caliber as they extend from the hila. The clinical value of daily routine chest radiographs in a mixed medical-surgical intensive care unit is low. The Macklin effect: A frequent etiology for pneumomediastinum in severe blunt chest trauma. Interstitial pulmonary emphysema in children and adults: Roentgenographic features. Distribution of pneumothorax in the supine and semirecumbent critically ill adult. Localized tension pneumothorax: Unrecognized form of barotrauma in adult respiratory distress syndrome. Thoracic computed tomography in intensive care patients-evaluation of clinical usefulness. Diagnosis of pulmonary embolism relies upon cautious utilization of the available tests in the right clinical setting, as the accuracy of the results of the investigations depends upon the pretest clinical probability. Embolism consisting of bland or infected thrombi, tumor cells, bone marrow, fat, injected foreign material and air may lodge in the pulmonary arterioles and arteries depending on their size. The sudden onset of unexplained dyspnea or tachypnea is the most frequent symptom of pulmonary emboli while pleuritic chest pain, hemoptysis and pleural effusion and pleural friction rub are present when infarction has occurred. Since the symptoms are nonspecific, clinicians have to rely on the investigations and imaging plays a crucial role in the timely diagnosis of this condition. Chest radiograph (B) in another patient shows a characteristic left sided Hampton hump (arrow). Serial chest X-rays also provide valuable information regarding the course of the disease.

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It is more frequent in adults and the incidence of concomitant pulmonary tuberculosis is high medicine zantac epitol 100 mg purchase without prescription. The classical sites could be head of humerus, glenoid, spine of the scapula, acromioclavicular joint, coracoid process and rarely synovial lesion. It can also be iatrogenic due to steroid injection given for a stiff shoulder with the mistaken diagnosis of frozen shoulder, particularly in diabetics. In the shoulder joint the initial tubercular destruction is typically widespread because of the small surface contact area of articular cartilage. The clinical presentation is with severe painful restriction of the shoulder movements, particularly abduction and external rotation, and gross wasting of shoulder muscles. The joint space involvement and capsular contracture are seen early in the disease. There is an atrophic type of tuberculosis of the shoulder in which the disease runs a benign course without pus formation called caries sicca and small pitted erosions on the humeral head may be seen. The classical dry type is more common in adults while the fulminating variety with cold abscess or sinus formation is more common in children. Magnetic resonance can show synovial lesions as well, besides the osseous lesions. Differential diagnosis includes periarthritis of the shoulder, rheumatoid arthritis and post-traumatic shoulder stiffness. Aspiration of the shoulder and fine needle aspiration biopsy might be necessary to establish the diagnosis. Radiographic features in articular type include involvement of humerus and ulna, osteoporosis, blurring of articular cortex and early diminution of joint space while in the extra-articular type, ulna is involved most commonly with destructive lesions seen in olecranon or coronoid process. Synovial thickening of the radiohumeral segment of the articulation can be present, particularly if the synovium is involved. In advanced cases there is decreased joint space and subchondral bone destruction. The diagnosis can be confirmed by aspiration or biopsy of synovium from the lateral side. Differential diagnosis includes osteochondritis dissecans of the humeral condyle and osteoid osteoma of the lateral condyle of the humerus which being intra-articular in location can be mistaken for tuberculosis of the elbow joint. All carpal bones tend to get involved in adults while more localized lesions are seen in children. Intense demineralization is present in carpus, distal radius and ulna, metacarpals being usually spared. Sacroiliac Joints these are affected more often in young adults than children and the involvement is usually unilateral.

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Complications medicine youtube 100 mg epitol purchase overnight delivery, Outcomes/Prognosis, Surveillance, Early and Late Failures the published literature on outcomes is scant and there are no level I data. Single-center series show promising results with no significant in-stent restenoses or thromboses in short- and midterm follow-up. Hematuria and pain may take up to 6 months to resolve, but some will show improvement or resolution within a week. Fortunately, thrombosis of the renal vein is extremely uncommon so thrombolysis is rarely necessary. Dozens of reports of use of balloon-expandable, self-expanding, or self-expanding covered stents have been published, mostly single case reports. Unlike cohesive neurovascular bundles elsewhere in the body, the subclavian vein courses through a different space than the artery and nerves, bounded by the first rib inferiorly, subclavius muscle and clavicle superiorly, costoclavicular ligament medially, and anterior scalene muscle posterolaterally. This space is restricted in the normal subject and the adjacent musculoskeletal structures do not move a great deal, but abduction and external rotation at the shoulder further narrow this space. Diameter of balloon and stent can be calculated according to the expected diameter of a cylinder based on the circumference of the compressed vein. Paget-Schroetter syndrome is uncommon, affecting an estimated 5,000 patients per year in the United States. Approximately twice as many men as women are diagnosed, and probably related to hand dominance, more right-sided disease is reported than left. Although venous impingement and "pinch-off" syndrome may play a role in commonly seen iatrogenic subclavian vein thrombosis after venous catheterization, dialysis access creation, or pacemaker lead placement, this should be distinguished from primary axillosubclavian vein thrombosis or Paget-Schroetter syndrome. Most of the literature promotes a combination of endovascular and open surgical treatment for Paget-Schroetter syndrome, exploiting endoluminal techniques for clearance of thrombus and extraluminal techniques for relief of musculoskeletal impingement. Large series document very high clinical success rates for early100,101 as well as delayed102,103 surgical decompression of the thoracic inlet. Techniques include transaxillary, supraclavicular, infraclavicular, paraclavicular, and laparoscopic methods of first rib resection; debulking of ligaments, muscles, fibrous bands, and osteophytes; and venolysis. However, there are also data suggesting that surgical decompression is not necessary in up to half of these patients, who become asymptomatic after thrombolysis, anticoagulation, and a period of restraint from the inciting activity. Venous access to the brachial or basilic vein peripheral to the thrombosis allows diagnostic venography and use of thrombectomy devices and/or thrombolysis infusion catheters. Success of thrombolysis depends on chronicity of clot, but unlike May-Thurner syndrome, the options of balloon venoplasty and stenting are controversial. Anatomic or Lesion Considerations, Technical/ Device Considerations the site of venous impingement in the thoracic inlet presents unique endovascular challenges. Patients may have hypertrophied muscles (subclavius, scalene), restrictive fibrous bands or ligaments (costoclavicular ligament, Roos bands107), supernumerary ribs, post-fracture calluses, or aberrant nerves (phrenic, brachial plexus) external to the vein contributing to impingement. Right upper extremity venography via brachial access in a 19-year-old woman weight lifter who presented with pain and swelling after a workout revealed acute thrombosis of the subclavian and duplicated axillary veins with poorly formed collateral channels draining into the external jugular system.

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The posterior portion is seen as a crescentic fluid collection posterior to the ascending aorta medicine used to treat chlamydia generic 100 mg epitol mastercard, usually at the level of the left pulmonary artery. The fluid in this posterior portion lies directly posterior to the aorta with no intervening fat. The crescent shape and fluid attenuation are other distinguishing features from lymph nodes. It is separated from the transverse sinus by a double reflection of the serous pericardium running between the right and left superior pulmonary veins. These may be distinguished by the fact that fluid lies both anterior and posterior to the veins whereas lymph nodes lie only on one side and may narrow the vein. The former lies inferior to the right pulmonary artery and is bounded by the pericardial reflection from the right pulmonary artery to the superior vena cava. Pericardial fluid is also seen in the anterior (black arrow) and right (white arrow) portions of the superior aortic recess. The effect is more pronounced on the right ventricle than on the left because of its thinner wall. This may be the result of its drooping into the cardiophrenic region when it originates higher up. On cross sectional imaging, it is a well-defined unilocular, thin walled homogenous nonenhancing mass contiguous with the pericardium. Occasionally, a cyst may contain proteinaceous contents, which may then have high signal intensity on T1 weighted images. A discriminative feature is the common tendency to change in size or shape with respiration or body position. If there is mass effect or enhancement, an alternative diagnosis should be sought. They can be found throughout the mediastinum but the most common location is the right anterior cardiophrenic angle. A pericardial cyst in an unusual location may be indistinguishable from a bronchogenic or thymic cyst. Pericardial defects are usually associated with defects in the parietal pleura through which lung can herniate. Associated congenital anomalies include anomalies of the heart (atrial septal defect, patent ductus arteriosus), lung (bronchogenic cysts, pulmonary sequestration), chest wall (pectus excavatum) and diaphragm. The left coronary artery may also be compressed leading to ischemia, especially during exercise.

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There may be some difficulty in differentiating between medial osteophytes and loose articular bodies in the acetabular fossa medications not to take after gastric bypass generic 100mg epitol with amex. A linear radiodense shadow favors osteophytes, whereas a circular intra-articular shape makes a loose body much more likely than an osteophyte. Exclusion of septic arthritis and neuropathic arthropathy is of critical importance preoperatively. Generally, the goal is to provide a tangential view of the weight bearing joint so that the thickness of the cartilage space can be assessed. The anteroposterior radiograph is obtained with the patient supine with the central ray directed 5 degrees in a cephalad direction. The tunnel view (a frontal view with the knee flexed about 50o) provides additional information about the intercondylar tubercles and the posterior surface of the femoral condyles. These views reliably show the extent of joint space loss and the degree of angulation and subluxation (varus or valgus). The tube should be angled 30 degrees toward the floor, (ii) Sunrise view-the patient lies in the prone position with the knee-flexed 90 degrees or more and the X-ray beam strikes the articular surface tangentially and so provides information about the joint space. The standing view of the legs is an important study for the evaluation of osteoarthritic deformity and is especially valuable for planning osteotomy correction. The patient stands with weight equally distributed on both legs and the patellae directed forward. In a normal individual, the mechanical axis (a line drawn from the center of the femoral head to the center of the ankle) passes just medial to the center of the knee-joint. Ahlback52 defined cartilage space narrowing on standing views as a cartilage space of less than 3 mm, or less than half the width of the same area in the opposite normal knee, the other compartment of the same knee, or by the presence of cartilage space narrowing on weight bearing as compared with nonweight-bearing views. Osteophytes Four areas of knee osteophyte formation have been described, marginal, intercondylar, tibial spine, and internal. Marginal osteophytes are frequently seen at the femoral and tibial margins of the joint as well as in advanced cases at the intercondylar tubercles. The central type of osteophytes, most common at the femoral condyles, can be misinterpreted as intra-articular bodies. Radiographic Findings the knee-joint can be divided into three compartments: the lateral femorotibial, medial femorotibial and patellofemoral compartments. In most cases only one or two of these compartments show evidence of osteoarthritic changes.

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Spontaneous atheromatous embolization: review of the literature and a report of 16 additional cases symptoms valley fever 100mg epitol buy with amex. Evaluation of aortic valve replacement with porcine xenograft without long-term anticoagulation. Blue toe syndrome: treatment with anticoagulants and delayed percutaneous transluminal angioplasty. Clinical aspects of persistent sciatic artery: report of two cases and review of the literature. Digital artery embolization as a result of fibromuscular dysplasia of the brachial artery. Vascular complications are not uncommon after solid organ transplantation and may lead to graft dysfunction and, ultimately, graft loss. Understanding the relative surgical anatomy, the causes and types of vascular complications, their presentation, and the options for therapy is important for managing solid organ transplant recipients. Endovascular management of these vascular complications also has had a growing role in managing these postoperative complications owing to the minimal invasiveness of the endovascular management and that these techniques usually do not preclude subsequent surgical bailout. Liver transplantation, in particular, is a large and complex surgery with two inflows (arterial and portal) and the hepatic venous outflow and invariable surgical anatomy. This article discusses the surgical anatomy, the postoperative vascular complications of liver transplantation, and the endovascular management options of these vascular complications. It is followed by another chapter discussing the vascular complications of renal and pancreatic transplants. Conduit materials usually include preserved arterial autologous grafts (iliac arteries usually) or venous conduits from cadaveric donors. Many other arteries and veins (even from the recipients) can be used, such as saphenous veins and radial arteries. Infrarenal aortohepatic conduits can be further classified into retroperitoneal anterior to the pancreas and posterior to the pancreas. Commonly, it is an end-to-end recipient portal vein to donor portal vein anastomosis. The donor portal vein can be the main portal vein of a whole cadaveric graft or the right main portal vein or left portal vein of split grafts (whether living or deceased donor grafts). The stump may be long and intact from harvesting and this makes an easier end-to-end portal anastomosis that is somewhat a distance from the porta hepatis and the portal bifurcation. If the graft/donor portal vein stump is short or damaged during harvesting, however, the anastomosis can be very close or even involve the portal bifurcation. In that instance, portal vein stenoses can be complex and involve the portal bifurcation. Another variable on the recipient side of the portal circulation is the presence of preexisting (pretransplant) left-sided (mesenterico-renal, mesenterico-caval, gastrorenal, gastro-caval) portosystemic collaterals. A detailed anatomy discussion is beyond the scope of this chapter; however, basic surgical anatomy is described to introduce the principles of liver transplant surgical anatomy. Steno-occlusive hepatic artery complications represent over 95% of arterial complications of the hepatic artery after liver transplantation.

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The imaging findings may reflect an absence of fungal invasion treatment rosacea buy epitol 100 mg without prescription, an altered inflammatory reaction within the infected disc, or an intrinsic characteristic of either the disc before infection. Fungal infections of the spine include aspergillosis, coccidioidomycosis, cryptococcosis, Candida and blastomycosis. Radiologically, each fungal infection does not have any distinctive features of its own. Most of them resemble tubercular infection, but a few characteristic features have been described for some of the infections. Cryptococcosis (Torulosis) Cryptococcosis is a serious disease of worldwide distribution caused by Cryptococcus neoformans, an organism that has Chapter 188 Nontubercular Infections of the Spine 3051 an unusual predilection for the central nervous system. This fungus can be recovered from soil, pigeon droppings, fruit, and human intestinal tract and skin. The disease is generally acquired by the respiratory route through inhalation of aerosolized spores. The development of Cryptococcus infection in patients with compromised immune defences is well known. Again, multifocal involvement and large paraspinal soft tissue abscesses may be present making the picture at times indistinguishable from tuberculosis. Skeletal changes can occur because of hematogenous seeding, or by direct extension from an overlying cutaneous lesion. The commonly affected osseous sites are the vertebrae, the ribs, the tibia, the carpus, and the tarsus. All age groups can be affected, but the disease appears to have a predilection for those in the second through fifth decades of life. Disseminated disease produces generalized symptoms of fever, malaise, anorexia, and night sweats. Vertebral involvement produces a destructive lesion often associated with a large paraspinal mass. Blastomycosis of the spine must be distinguished from tuberculosis and coccidioidomycosis. In tuberculosis the posterior elements of the vertebral body are not infected, whereas in coccidioidomycosis and blastomycosis all bony elements of the spine may be involved. Candidiasis (Moniliasis) Of the various Candida species, Candida albicans is most commonly associated with human disease. Candida infection of the musculoskeletal system occurs typically in intravenous drug addicts and when host resistance is depressed. Radiographic findings include soft tissue swelling, joint space narrowing, irregularity of subchondral bone, and more widespread changes of osteomyelitis. Aspiration of synovial fluid or biopsy of synovial membrane with isolation of Candida confirms the diagnosis. The principal host is the dog, whereas sheep and humans are the intermediate hosts.

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Quadir, 54 years: Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Recently introduced Indium 111 labeled polyclonal immunoglobulin (IgG) has the highest sensitivity and specificity of 92% and 95100%, respectively. Congenital hypothyroidism is characterized by delayed skeletal maturation with bone age lagging behind the chronological age.

Sibur-Narad, 36 years: The above radiographic findings in the axial and appendicular skeleton are distinctive and the diagnosis may be suggested prior to the clinical recognition of the disorder. It invariably occurs in the parietal pleura, whereas when secondary to pyothorax or hemothorax, it may be confined to the visceral pleura. Opacities range from a groundglass appearance with indistinct margins, to reticular or reticulonodular, to consolidation with air bronchograms.

Hamil, 31 years: They may contain ectopic gastric mucosa and 99mTc sodium pertechnetate may be useful in their diagnosis. The second time interval extends from 1 month to 2 years following insertion of graft. In papulopustular eruption, patients may find a low-grade reaction very significant, given its impact on their quality of life.

Einar, 47 years: Acute myocardial infarction: intracoronary application of nitroglycerin and streptokinase. However, most interventions require catheterization of the abnormal hepatic veins. If patients have hyperkeratotic areas on the feet at baseline, referral to a podiatrist is warranted.

Torn, 46 years: Management of non-occlusive hepatic artery complications after liver transplantation. Provided these conditions are met, embolization of nasopharyngeal hemorrhage yields rewarding therapeutic and clinical results. Increased Air with Unchanged Blood and Tissue this group of disease is exemplified by ostructive overinflation without lung destruction.

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