Heather J. Frederick MD

  • Assistant Professor
  • Department of Anesthesiology
  • Duke University Medical Center
  • Durham, North Carolina

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Decreased attenuation in the brain surrounding the abscess represents axonal edema heart attack cover by sam tsui and chrissy costanza of atc trusted 2.5 mg lisinopril. Axial images in two different patients show poorly defined zones with low attenuation in the left cerebral hemisphere from Aspergillus infection (a) and in the upper right frontal lobe from Mucor infection (b). Lesions can have decreased attenuation, central zone of low attenuation with a thin peripheral rim of intermediate attenuation, with solid or rim pattern of contrast enhancement, with or without calcification. Single or multiple solid and/or ring-shaped lesions located in basal ganglia and/or corticomedullary junctions in cerebral hemispheres, low to intermediate attenuation, nodular or rim pattern of contrast enhancement, with or without peripheral low attenuation (edema). Echinococcus multilocularis: Cystic (with or without multilocular) and/or solid lesions; central zone of intermediate attenuation surrounded by a slightly thickened rim of low to intermediate attenuation, with contrast enhancement; peripheral zone of low attenuation (edema) and calcifications are common. Lesions can be located in the cerebral or cerebellar white matter, brainstem, and basal ganglia; Contrast enhancement can be ringlike; usually in acute/early subacute phase of demyelination. Comments Occurs in immunocompromised patients and in inhabitants of developing countries. Other demyelinating diseases are acute disseminated encephalomyelitis/immune mediated demyelination after viral infection, toxins, or metabolic disorders. Usually occurs from 4 to 6 months to 10 y after radiation treatment; may be difficult to distinguish from neoplasm. Gliosis (low to intermediate attenuation) allows differentiation from schizencephaly. Cyst walls have histopathologic features similar to epithelium, neuroepithelial cysts located in choroid plexus choroidal fissure ventricles brain parenchyma. Circumscribed tumors with or without disseminated disease; pineal region suprasellar region third ventricle/basal ganglia; low to intermediate attenuation; with contrast enhancement of tumor and leptomeninges if disseminated. Usually histologically benign but locally aggressive lesions arising from squamous epithelial rests along the Rathke cleft; occur in children (10 y) and adults (40 y), males females. Axial postcontrast image shows a ring-enhancing tuberculous abscess involving the brainstem, as well as a nodular-enhancing lesion in the basal meninges. Axial image shows a cyst adjacent to the frontal horn of the right lateral ventricle in a patient with hydrocephalus and periventricular leukoencephalopathy. Postcontrast sagittal image shows a complex cystic and solid lesion in the suprasellar cistern. Coronal postcontrast fat-suppressed, T1weighted image (b) shows abnormal tumoral enhancement in the suprasellar cistern and third and lateral ventricles, as well as the septum pellucidum.

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It runs through the posterior triangle of the neck and can be injured during surgery at this location (lymph node biopsy) and causes medial winging of the scapula pulse pressure 29 discount lisinopril 2.5 mg online. The six divisions merge to form three cords related to the second part of the axillary artery Multiple Branches. Remember the 355 rule; the only exception is the branch from the trunks, being only one. Sural nerve (S1, S2) the sural nerve descends on the posterior surface of gastrocnemius and unites with the peroneal communicating nerve (communicating branch from the common peroneal nerve). It runs down alongside the saphenous vein behind the lateral malleolus and ends on the lateral side of the little toe. It is 538 Chapter 24: Anatomy oral core topics Supraclavicular branches (from roots and upper trunk) Roots (3 nerves) 1. Long thoracic nerve (C5, C6, C7): supplies serratus anterior muscle (nerve damage causes scapula winging). Enters the axilla by passing down over the lateral border of the first rib behind the axillary vessels. Arises in the posterior triangle of the neck and runs downwards and laterally inferior to trapezius and omohyoid. Enters the suprascapular fossa by passing through the suprascapular notch beneath the superior transverse scapular ligament. Compression in the suprascapular notch causes wasting of supraspinatus and infraspinatus muscles. The suprascapular nerve also sends some filaments to supply the shoulder joint and capsule. Descends posterior to clavicle and anterior to the brachial plexus and subclavian artery. May give a contribution to the phrenic nerve (C5), named the accessory phrenic nerve if present. It arises obliquely behind the lower fibres of pectoralis minor, lying lateral to the axillary artery and passes between the two conjoined heads of coracobrachialis. It runs laterally between biceps and brachialis adherent to the deep surface of biceps. It pierces the deep fascia, continuing on as the lateral cutaneous nerve of the forearm (lateral to the cephalic vein) supplying skin on the lateral aspect of the forearm. The axillary nerve is just inferior to the shoulder capsule and it is protected during shoulder surgery by adduction and external rotation of the arm.

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Nerves Anatomy Wallerian degeneration Axon and myelin degraded and removed by phagocytosis Existing Schwann cells proliferate Nerve cell body swells up and enlarges Rate of structural protein synthesis increases hypertension benign lisinopril 5 mg order line. Somatosensory evoked potentials Stimulation of a peripheral nerve (median or posterior tibial is standard) Electrical recordings at scalp electrodes are very small, therefore averaged over 100 or 200 stimulations Used for intraoperative monitoring of cord function Not absolute. Neurophysiological tests It is well worth visiting a neurophysiologist and observing how neurophysiological studies are performed. Nerve conduction studies these use stimulating and recording electrodes and a ground electrode. You should be able to relate the anatomical structure of the meniscus to its function. Examination corner Basic science oral 1 During a partial meniscectomy you excise part of the meniscus to its rim. The answer to this question will explore the concept of hoop stresses and how these are resisted by the ultrastructure and gross anatomical features of the meniscus. Basic science oral 2 What is the main type of collagen found in the meniscus of the knee Can you describe the microscopic arrangement of the collagen fibres within the meniscus and relate this to meniscal function This again requires the candidate to draw together aspects of the microstructure of the meniscus with the mechanical functions of the meniscus. Basic science oral 3 What are the contributions of the meniscus to knee function and how does it achieve these contributions This question can lead to various different discussions, ranging from the kinematics of the knee to loads on articular cartilage and nutrition of the articular cartilage. Shock absorption the presence of intact menisci reduces the peak forces on the articular cartilage and underlying bone from impacts by approximately 20%. Lubrication and nutrition the increased conformity of the surfaces contributes to nutrition and probably also to the lubrication of the joint. In young patients it is a hydrated gel Collagen in disc has high proportion of cross-links. Function the intervertebral disc forms part of the functional spinal unit: disc, facet joints, vertebral end plates and ligaments the disc must be able to resist compression, bending, shear and torsional (rotational shear) forces Compressive forces on the disc are greater when sitting than when standing Proteoglycans resist compressive forces (resulting from body weight above disc and action of paraspinal muscles) Collagen fibres resist tensile forces 461 Section 8: the basic science oral Under compression the nucleus pulposus resists the force by converting it in to radial forces, which are resisted by circumferential hoop stresses in the annulus fibrosus Twisting and tensile forces are resisted by the oblique arrangement of the collagen fibres in the lamellae of the annulus fibrosus Without the pressure within the nucleus pulposus the annulus fibrosus can buckle, impairing its mechanical properties Disc is less stiff at low loads than at high loads Hysteresis decreases with repeated loading, thus reducing ability to withstand further load cycles.

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Simple palpation is usually enough; however arteriosclerotic heart disease generic lisinopril 5 mg buy online, if dissection is difficult and the nerve cannot be palpated, exposure of the nerve may be indicated. The arm is then held in external rotation as this will draw the lesser tuberosity away from the axillary nerve, and the tendon is divided 2 cm from its lateral attachment on to the lesser tuberosity of the humerus. The capsule is now exposed and a plane developed between the capsule and subscapularis, which is best developed inferiorly. One can incise the subscapularis tendon vertically or perform a horizontal subscapularis muscle-splitting approach. A subscapularis muscle-splitting approach is sometimes performed to decrease the risk of muscle shortening and failure of healing of the tendon repair. To gain better exposure, a pectoralis major tenotomy can be performed at the superior third of its insertion and the deltoid can be partially released from the clavicle. Internervous plane the internervous plane lies between the deltoid muscle (axillary nerve) and the pectoralis major muscle (medial and lateral pectoral nerves). Superficial dissection the incision is deepened through subcutaneous fat to the fascia overlying the deltoid and pectoralis major muscles. The fat is swept back with a swab to help identify the deltopectoral groove, marked by the large cephalic vein. Failure to find this internervous plane can lead to a difficult dissection through the deltoid and can lead to denervation of the anterior portion of the deltoid. Cauterize the deltoid branches of the thoracoacromial artery, which lie in the deltopectoral groove. Retract the cephalic vein laterally and open the deltopectoral interval by blunt dissection and insert a self-retaining retractor. Alternatively, sometimes taking the cephalic vein medially allows an easier dissection (sometimes the vein just wants to go medially). If the cephalic vein is injured during dissection, ligate it proximally and distally. Laterally reflect the anterior part of the deltoid muscle to expose structures about the coracoid process and the anterior part of the joint capsule. The coracoid process with attached muscles (coracobrachialis, pectoralis minor and short head of biceps) is now exposed. Perform either an osteotomy of the coracoid process or, more simply, leave the coracoid process intact and retract the attached muscles medially. Retractors placed under the conjoint tendon can cause neuropraxia of the musculocutaneous nerve; vigorous retraction must be avoided.

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Hence blood pressure up after exercise lisinopril 10 mg buy on-line, open reduction and plate fixation of distal radius fracture via a volar approach is performed. If this is well reduced and stable, then an above-elbow cast with the wrist in supination is applied. If the distal radioulnar joint is reducible but unstable, then percutaneous wire fixation of the distal radioulnar joint and above-elbow cast with wrist in supination is applied. If the distal radioulnar joint is unreducible, then open reduction of the joint is performed. Often there is interposed soft tissue (often extensor carpi ulnaris), after removal of which the joint reduces and is stabilized with wires, and an above-elbow cast with wrist in supination is applied. Fractures are presumed to be unstable if radial shortening >5 mm, dorsal angulation >20 and intra-articular fragment depression >2 mm. Over time ligamentotaxis effect may be compromised owing to viscoelastic properties of ligaments. After any surgical stabilization, always assess the distal radioulnar joint and scapholunate joint stability. Complications Infections, wrist stiffness and late displacement of distal radioulnar joint (in fractures treated in a cast). For example, if the deep posterior compartment of the calf is to be tested then passive extension of interphalangeal joints of all the toes should be performed, not passive extension of the ankle. Any movement of the ankle in a tibia fracture is bound to produce pain and this could be confused with compartment syndrome. Difficulties in clinical assessment of compartment syndrome occur in unconscious patients or in polytraumatized patients or with nerve injuries or blocks. Under these conditions or when diagnosis is doubtful, measuring compartment pressures with a slit catheter (slit to reduce risk of blockade of catheter) or pressure transducer is helpful. Continuous or serial monitoring gives a better picture of an evolving condition rather than a one-off measurement. One-off measurements of all compartments separately could be performed but, if continuous monitoring is considered, the transducer tip should be as close as possible to the fracture. Delta pressure is the difference between diastolic pressure and compartment pressure.

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Still other patients may develop one or more giant hypertension questions cheap lisinopril 5 mg buy on-line, intractable ulcers in the Roux limb due to chronic ischemia, necessitating aggressive medical or even surgical management. Unlike gastric bypass, however, laparoscopic bands require multiple adjustments with individual tailoring of the bands. As the bands are slowly tightened, gastric volume is restricted, leading to early satiety and weight loss. The procedure entails laparoscopic placement of a silicone band around the proximal stomach, creating a small gastric pouch. The band is slowly tightened by incremental administration of saline via a subcutaneous port connected by tubing to the band. Some surgeons adjust the band under fluoroscopic guidance in the radiology department. Note how the gastric band narrows the lumen of the proximal stomach with the formation of a small gastric pouch above the band. The band is connected via tubing to a subcutaneous port that can be used to administer or withdraw fluid from the band, varying the degree of luminal narrowing. In one series, 7% of routine band adjustments were considered to be tight on the initial barium study, necessitating readjustment of the band to prevent the development of obstructive symptoms. Late complications include port complications with disruption of the port catheter or catheterband connection, stomal stenosis, acute food impaction above the band, distal band slippage, and, rarely, gastric volvulus or even intraluminal band erosion. This complication occurs when the band migrates distally or the stomach prolapses proximally through the band, so the proximal gastric pouch extends more than several centimeters above the band. Distal band slippage is usually associated with luminal narrowing and obstruction by the band. Distal slippage may be reversible if all residual fluid is removed from the band, but if the slippage persists even after the fluid has been withdrawn, the band should be removed surgically. Gastric volvulus is a rare complication of bands precipitated by distal slippage of the band or proximal prolapse of the stomach through the band. Gastric volvulus occurs when the prolapsed portion of the stomach twists around the band, causing a high-grade, often closed-loop obstruction that can be detected on barium studies. The initial barium study after administration of saline in to the band shows marked luminal narrowing (short black arrows) by the surrounding band (long black arrows) with mild dilatation of the gastric pouch (long white arrow) and distal esophagus (short white arrows) above the band and slow emptying of barium in to the remaining stomach. A repeat barium study after withdrawal of some of the previously administered barium shows considerably less luminal narrowing (short black arrows) by the band (long black arrows) with less distention of the gastric pouch (long white arrow) and distal esophagus (short white arrows) above the band and better emptying of barium in to the remaining stomach. This patient most likely would have developed obstructive symptoms if the band had not been readjusted on the basis of the radiographic findings. A barium study shows distal slippage of the band (black arrows), which surrounds the upper body of the stomach. There also is marked luminal narrowing (white arrow) by the band with distention of the gastric pouch above the band and slow emptying of barium in to the remaining stomach. A barium study shows distal slippage of the band (black arrows), with marked narrowing and obstruction of the gastric antrum (small white arrow) where it traverses the band.

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Revision courses can be very motivating blood pressure bottom number high purchase lisinopril 10 mg mastercard, but you should realize that most of the courses are more difficult than the real exam and of course very expensive. I recommend taking this course as soon as you complete part 1, well in advance of part 2. It gives a very good idea of how to prepare for both the orals and the clinical examination. The only other course I attended was the viva practice course run by candidates who had recently passed the exam. This was coordinated by Sharma at Glasgow just before the real exam, and was very useful boosting my confidence and helping me refine my technique in answering viva questions. There are other courses mainly for basic sciences and a few courses concentrating on specific topics. The popular ones are booked well in advance and attending any one course provides an idea, but trying to attend all of the courses is a waste of time. This is a list of a few good courses: Stanmore and Cambridge basic science course. You should read well before going to the course and the viva practice is good the Wrightington hand course is a good alternative to not having done a formal posting. It covers almost all the exam short cases and viva topics on the hand the Oswestry, Edinburgh and Sheffield clinical examination courses. Examination the exam in general is to see if you are ready to be a day 1 general orthopaedic consultant, able to make safe, sensible decisions. It is essential to remember that you are not expected to know everything, but should be able to understand the principles of management. Each oral station carries a pass mark of 72, and there is a minimum of three topics by each examiner, with 12 marks for one topic, giving a total of 288. This is only for you to understand the clinical situation and, in general, the examiners take you through the questions with a smooth transition. The next question always depends on your answer to the previous question and, if you are completely erratic, the level of the question is dropped down, so you can still reach a 6. So, if you get it wrong on one question, it is best to leave it behind and try to score better in the next one as you have a total of 24 topics in the oral section. However, each point in the clinical case is much higher and therefore you must ensure that you are slick and thorough in your examination techniques. I was told that a pass is compulsory in the intermediate cases, but I think it is rather that it is 573 Section 9: Miscellaneous topics You should also check with your local deanery because all trainees are given viva practice by the consultants out of hours and I heard that they are more useful than any formal courses. Papers Most people are asked viva questions based on some of the recent Journal of Bone and Joint Surgery publications, but papers themselves are not discussed. Remember, if you are asked about papers, you should have got a 6 already and the extra point will cover for other mishaps. You will notice that a few clinical conditions keep repeating and knowing these in detail will allow you to score a more than average pass mark in a few sessions, which can compensate for a poor session elsewhere.

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The American Burn Association has devised specific referral criteria for transfer to specialized burn centers blood pressure normal heart rate high purchase lisinopril 10 mg fast delivery, which have been shown to decrease mortality and improve functional outcome of patients. Burn mortality has decreased drastically over the past three decades as a result of early excision and grafting, control of sepsis, advances in ventilatory and nutritional support, and wound care adjuncts such as synthetic skin substitutes. Therefore a focused examination is important to determine the possibility of neurologic or musculoskeletal injury. The patient should be completely exposed to assess for the extent of burn, and for evidence of any associated trauma. Proper initial resuscitation is dependent on accurate assessment of both the extent and depth of burn. In this calculation, the head and each upper extremity is 9%, while the lower extremities, the anterior and posterior trunks are each 18% of the body surface area. The lower extremities are 14% each with the remaining distribution the same as adults. Deeply burned skin looses elasticity and manifests as a loss of compliance in response to underlying tissue swelling. Though the initial chest radiographs may be normal in early inhalation injury, it may demonstrate parenchymal abnormalities such as pulmonary edema. These procedures can be done at the bedside to further evaluate the airways of patients with suspected inhalation injury. Visualization of airway erythema, edema, carbonaceous sputum, and singed nose hair all signify inhalation injury. Extensive burns of the extremities and subsequent edema make peripheral pulses difficult to palpate, and Doppler stethoscope may help detect weak pulses. Whenever suspected, objective measurements can assist in further clinical management. Glycemic control can reduce osmotic diuresis and infectious complications, and may improve survival. Although, the precise target range is yet to be defined, most practitioners attempt to keep glucose below 180 mg/dL. Similarly, circumferential burns of the extremities can impede blood flow and induce limb ischemia. Clinical vigilance and early escharotomy are imperative to prevent respiratory compromise or further tissue ischemia.

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Cronos, 57 years: Active peristalsis is maintained in the ileal segment, which propels urine in to the collection bag. Open up the interval between the tensor fascia lata laterally and sartorius medially. Note how polyps on the dependent or posterior wall appear as filling defects in the barium pool (black arrows), whereas polyps on the non-dependent or anterior wall are etched in white (small white arrows).

Sanuyem, 48 years: The double contrast esophagogram is therefore a biphasic examination; the double contrast phase optimizes detection of mucosal abnormalities, whereas the single contrast phase optimizes detection of strictures or subtle areas of narrowing. Median nerve in proximal forearm to ulnar nerve in middle/distal third of forearm. Elderly Generally, the adult dose can be used, but body weight should be considered.

Rendell, 44 years: Radial (lateral) collateral ligament this is a triangular band, the apex of which is attached to the lateral epicondyle of the humerus. Patient should remain recumbent during and for 15-30 min after medication administration. Cervicomedullary myelopathy and/or hydrocephalus can result from a narrowed foramen magnum.

Ur-Gosh, 40 years: Prevention of ischemic complications in patients with unstable angina or non-Q-wave myocardial infarction (use with concurrent aspirin therapy). Three-hour infusion-60 mg infused over 60 min (with 6-10 mg administered as a bolus over the first 1-2 min), followed by 20 mg/h infusion for the next 2 h to deliver a total dose of 100 mg. It is often difficult to obtain adequate open-mouth views of C-1 and C-2 in children because of their small mouths and inability to cooperate.

Emet, 25 years: Hydroflumethiazide (hydroflumethiazide, Diucardin, Saluron) Indications Edema Hypertension Dosage Adults Edema Initiate at 50 mg once or twice a day. The differential diagnosis list of diseased temporal bone is discussed in Tables 5. Lesions can have decreased attenuation, central zone of low attenuation with a thin peripheral rim of intermediate attenuation; with solid or rim pattern of contrast enhancement; with or without calcification.

Mortis, 30 years: Clinical features of rickets the clinical features depend on the severity of the deficiency and the age of onset. A B jejunostomy tube is normally distal to the site where the tube enters the small intestine. Occasional vascular injury may occur in a branch of the dorsalis pedis artery, which forms the plantar arch.

Trompok, 43 years: Plain chest and neck films: They can diagnose foreign bodies, fractures, pneumothorax, subcutaneous emphysema, and hematomas. Usually involves the middle facet of the subtalar joint TC coalitions account for approximately one-third of tarsal coalitions Pain in the medial side of the subtalar joint, repeated ankle sprains. If there is associated elbow dislocation, then direction of dislocation is assessed.

Givess, 21 years: A transverse collar incision is made at the appropriate level of vertebral pathology from the midline to the posterior border of sternocleidomastoid muscle. Unloading beyond the yield point will result in a linear plot parallel to the initial linear component of the plot but not returning to the intersection of the x and y axes. An incarcerated hernia means that the hernia cannot be reduced by physiological or extrinsic physical pressure.

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